Introduction to Network Meta-Analysis
09:00 - 16:00
Professor Nicky Welton is Professor in Statistical and Health Economic Modelling at the University of Bristol.
Dr Deborah Caldwell is Senior Lecturer in Public Health Research at the University of Bristol.
Ms. Edna Keeney is Senior Research Associate in Health Economics and Evidence Synthesis at the University of Bristol.
Course aims and objectives
By the end of the course participants should be able to:
- understand what indirect comparisons and network meta-analysis (NMA) are and why they are used;
- perform indirect comparisons using Stata;
- perform network meta-analysis using Stata, with continuous and dichotomous data;
- understand how NMA can be used to pool evidence on complex interventions, and the assumptions required to do so;
- understand the assumptions made in NMA and use Stata to examine consistency;
- be aware of different techniques to present the results from NMA;
- be able to critically appraise a paper that uses NMA.
Who the course is intended for
This course is designed for health services researchers, health psychologists, epidemiologists, statisticians, systematic reviewers and decision analysts.
Prerequisites - Experience of meta-analysis (ideally in Stata), and knowledge of statistical methods including logistic regression. An understanding of research design would also be helpful.
- Meta-analysis in Stata (refresher).
- Introduction to indirect comparisons, and combining direct and indirect evidence.
- Performing indirect comparisons in Stata, including practical.
- Introduction to network meta-analysis.
- Performing NMA in Stata, including practical.
- Systematic review to inform NMA.
- Assumptions, ground rules and FAQs for network meta-analysis.
- NMA using other outcomes.
- Pooling evidence on complex interventions using NMA
- Assessing Inconsistency in NMA.
- Explaining and Presenting Results.
- Reporting and critical appraisal of NMA, including group work.
Location: CA112, Cairnes Building
DAY 1: Thurs 16th August 2018
09:00-10:00 Meta-Analysis in Stata Deborah Caldwell
10:00-11.15 Introduction to Indirect Comparisons + practical Edna Keeney
11:45-12:45 Introduction to Network Meta-Analysis Nicky Welton
13:45-14:45 NMA in Stata Nicky Welton Nicky Welton
15:00-16.00 NMA Practical All
16.00-17.00 Systematic Review for NMA Deborah Caldwell
DAY 2: Fri 17th Aug 2018
09.00-10.00 Systematic Review exercise Deborah Caldwell
10.00-11.00 Other outcomes and data formats Nicky Welton
11:15-12:30 NMA for Complex Interventions Deborah Caldwell / Nicky Welton
13:30-14.30 Inconsistency checking Nicky Welton
14.30-15.30 Interpreting, presenting and reporting results of NMA Edna Keeney
15.45-16.30 Group work – critical appraisal/ reporting of NMAs Edna Keeney